WP4: Multiscale Numerical Simulation

Adapt a biological model of thrombosis and a Lattice Boltzmann model for blood flow and merge into a multiscale model of thrombosis in cerebral aneurysms, using the Complex Automata approach. Validate and calibrate the numerical model by comparing simulations with in-vitro and in-vivo observations, focussing on the evolution and the nature of thrombus formed in stented aneurysms. Develop an optimization tool to explore the design space of flow modifier stents.

Leader: Bastien Chopard - UNIGE, Partner 2.